{"id":3970,"date":"2025-07-16T14:36:57","date_gmt":"2025-07-16T12:36:57","guid":{"rendered":"https:\/\/www.tzdo.de\/?p=3970"},"modified":"2026-04-22T14:35:04","modified_gmt":"2026-04-22T12:35:04","slug":"erfolgreiche-entwicklung-eines-therapeutischen-antikoerpers-bei-der-lead-discovery-center-gmbh-aus-dem-biomedizin-zentrum-dortmund","status":"publish","type":"post","link":"https:\/\/www.tzdo.de\/en\/erfolgreiche-entwicklung-eines-therapeutischen-antikoerpers-bei-der-lead-discovery-center-gmbh-aus-dem-biomedizin-zentrum-dortmund\/","title":{"rendered":"Successful development of a therapeutic antibody at the Lead Discovery Center GmbH from the Biomedical Centre Dortmund"},"content":{"rendered":"<p>The biotech start-up EvlaBio secures seed financing totalling 21 million euros. This makes this seed financing round one of the largest of its kind for a biotechnology company in Germany. This success was made possible by the development of a specific therapeutic antibody at the Lead Discovery Center GmbH (LDC), a translational research company at the Biomedical Centre Dortmund (BMZ). Photo: Lead Discovery Centre<\/p>\n<p>The aim of the start-up company EvlaBio, based in D\u00fcsseldorf and Zurich, is to develop a monoclonal antibody for the treatment of left ventricular hypertrophy (LVH) in patients with chronic kidney disease (CKD).<\/p>\n<p>\"Despite medical advances, there is still a significant clinical need in the treatment of LVH in the context of CKD. Our technology intervenes directly at the cardiomyocyte level in a pathologically active signalling pathway and has the potential to improve the quality of life of millions of people affected,\" explains Wenzel von der Heydte, CEO and co-founder of EvlaBio.<\/p>\n<p>The EvlaBio research programme was originally initiated by the LDC, a spin-off of Max Planck Innovation, and further developed together with the KHAN Technology Transfer Fund I.<\/p>\n<p>The seed round was led by Kurma Partners, AdBio Partners, Boehringer Ingelheim Venture Fund, NRW.Venture (NRW.BANK) and HTGF and will enable EvlaBio to complete preclinical development and progress towards IND-approvable studies.<\/p>\n<p><a href=\"https:\/\/evlabio.com\/home\">Here you can find the press release of EvlaBio.<\/a><\/p>\n<p><strong>About Lead Discovery Centre GmbH<\/strong><\/p>\n<p>Since the foundation<span>\u00a0In 2008, LDC r<\/span>and 130 drug discovery projects launched. LDC<span>\u00a0<\/span>a<span>\u00a0<\/span>Paving the way for innovative medicines<span>\u00a0<\/span>for diseases with a high medical need.<\/p>\n<p>As a translational drug discovery company, LDC takes promising innovative research projects and, together with over 100 academic partners, transforms them into medically and commercially attractive drug candidates.<\/p>\n<p><a href=\"https:\/\/www.lead-discovery.de\/de\/\">Click here to go to the LDC website.<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>The biotech start-up EvlaBio secures seed financing totalling 21 million euros. This makes this seed financing round one of the largest of its kind for a biotechnology company in Germany. This success was made possible by the development of a specific therapeutic antibody at the Lead Discovery Center GmbH (LDC), a translational research company at the Biomedical Centre Dortmund (BMZ). Photo: Lead...<\/p>","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3970","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Erfolgreiche Entwicklung eines therapeutischen Antik\u00f6rpers bei der Lead Discovery Center GmbH aus dem Biomedizin Zentrum Dortmund - TechnologieZentrumDortmund<\/title>\n<meta name=\"description\" content=\"Das Biotech-Startup EvlaBio sichert sich eine Seed-Finanzierung in H\u00f6he von 21 Millionen Euro. 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